The Influence of Synthesit on Cholesterol Levels

Wellness
Heart & vessels
Anti-age

Patrik Kusnir1, Shahbaz Baig2

1. Research and Development, Synthesit Swiss SA, Genève, Switzer Land.

2. Professor, Department of Community Medicine, Independent Medical College, Faisalabad.

A research published in the Journal of the University Medical and DentalCollege highlights the clinical aspects of the mineral Synthesit's effect oncholesterol levels.

The research was conducted by Patrick Kushnir, aresearcher and developer at Synthesit Swiss SA (Geneva, Switzerland), andShahbaz Baig, Professor at the Department of Community Medicine, IndependentMedical College (Faisalabad, Pakistan). The study involved a 69-year-oldpatient with dyslipidemia from Sevastopol, Russia.

Key results 

The research showed that the intake of Synthesit leads to these results:

  1. Initial cholesterol reduction. After starting the supplementation, asignificant decrease in serum cholesterol levels was observed.
  2. Moderate cholesterol elevation with prolonged use. Cholesterol values increased slightly over time.

These results highlight the need for further research to understand the long-term effects of Synthesit on lipid metabolism and its potential application in the treatment of dyslipidemia.

Role of iron in lipid metabolism

The interaction of iron with lipid metabolism plays a key role in the metabolic processes of the body. The research revealed the following aspects:

  • Iron as a regulator of lipid metabolism. An imbalance in iron levels in the body can negatively affect lipid pathways, leading to neurodegenerative diseases and hyperlipidemia;
  • Linking iron to oxidative stress. Iron reduces oxidative stress, but its excess can lead to lipid peroxidation, increased levels of inflammatory cytokines, and impaired cholesterol metabolism;
  • Role of ferritin. Serum ferritin levels are a key marker for assessing iron accumulation and its effect on metabolism.

Clinical significance

According to these researches, elevated ferritin levels are linked with:

  • Decreased likelihood of atherosclerosis;
  • Reduced incidence of diseases caused by high cholesterol;
  • An association with insulin resistance and risk of type 2 diabetes mellitus.

Conclusion

Synthesit has shown potential for use in the regulation of cholesterol levels. Larger clinical trials are needed to evaluate the efficacy of the supplement in the long term.

Effect of Synthesit on serum cholesterol levels

Case Report

Liver tissue of a typical histological structure

(hematoxylin and eosin coloring, x400 scaling)

Myocardial tissue of a typical histological structure

(hematoxylin and eosin coloring, x400 scaling)

Kidney tissue of a typical histological structure

(hematoxylin and eosin coloring, x400 scaling)

Lung tissue of a typical histological structure

(hematoxylin and eosin coloring, x400 scaling)

Bone marrow of a mouse not taking iron citrate

(hematoxylin and eosin coloring, x400 scaling)

Bone marrow of a mouse taking iron citrate

(hematoxylin and eosin coloring, x400 scaling)
THE CONTROL

A smear imprint of the bone marrow of a mouse not taking iron citrate

(May-Grunwald-Giemsa coloring, cytological micropreparation, scaling x400)
THE EXPERIMENT

A smear imprint of the bone marrow of a mouse taking iron citrate

(May-Grunwald-Giemsa coloring, cytological micropreparation, scaling x400)
THE CONTROL

A smear imprint of the bone marrow of a mouse not taking iron citrate

(May-Grunwald-Giemsa coloring, cytological micropreparation, scaling x1000)
THE EXPERIMENT

A smear imprint of the bone marrow of a mouse taking iron citrate

(May-Grunwald-Giemsa coloring, cytological micropreparation, scaling x1000)
INDICATORS
CONTROL GROUP
EXPERIMENTAL GROUP
Total myelokaryocyte amount (on the thigh),mln
15,0 ± 0,9
*22,2 ± 1,2
Reticular cells
1,3 ± 0,1
*1,5 ± 0,1
Non-deferred blasts(monocular cells)
2,2 ± 0,1
*5,4 ± 0,1
Myeloblasts
2,1 ± 0,1
*3,5 ± 0,1
Myeloid cell mitosis
0,1 ± 0,0
*0,2 ± 0,0
Lymphocytes
16,8 ± 1,8
*22,0 ± 1,1
Megakaryocytes
0,3 ± 0,0
*1,1 ± 0,1
Erythroblasts
0,5 ± 0,1
*1,9 ± 0,1
*statistically significant difference compared with the control group.

Other researches & sertifications

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